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A distinct role for recombination repair factors in an early cellular response to transcription–replication conflicts

Transcription–replication (T–R) conflicts are profound threats to genome integrity. However, whilst much is known about the existence of T–R conflicts, our understanding of the genetic and temporal nature of how cells respond to them is poorly established. Here, we address this by characterizing the...

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Detalles Bibliográficos
Autores principales: Shao, Xin, Joergensen, Amalie M, Howlett, Niall G, Lisby, Michael, Oestergaard, Vibe H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261159/
https://www.ncbi.nlm.nih.gov/pubmed/32329774
http://dx.doi.org/10.1093/nar/gkaa268