Cargando…
Emergence of a novel immune-evasion strategy from an ancestral protein fold in bacteriophage Mu
The broad host range bacteriophage Mu employs a novel ‘methylcarbamoyl’ modification to protect its DNA from diverse restriction systems of its hosts. The DNA modification is catalyzed by a phage-encoded protein Mom, whose mechanism of action is a mystery. Here, we characterized the co-factor and me...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261163/ https://www.ncbi.nlm.nih.gov/pubmed/32369169 http://dx.doi.org/10.1093/nar/gkaa319 |