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H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes

In mammalian cells, distinct H3K4 methylation states are created by deposition of methyl groups by multiple complexes of histone lysine methyltransferase 2 (KMT2) family proteins. For comprehensive analyses that directly compare the catalytic properties of all six human KMT2 complexes, we employed a...

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Detalles Bibliográficos
Autores principales:	Kwon, Minjung, Park, Kihyun, Hyun, Kwangbeom, Lee, Jeong-Heon, Zhou, Linjiao, Cho, Young-Wook, Ge, Kai, Skalnik, David G, Muir, Tom W, Kim, Jaehoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261165/ https://www.ncbi.nlm.nih.gov/pubmed/32365172 http://dx.doi.org/10.1093/nar/gkaa317

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