Cargando…

Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends

The histone H3 variant CENP-A marks centromeres epigenetically and is essential for mitotic fidelity. Previous crystallographic studies of the CENP-A nucleosome core particle (NCP) reconstituted with a human α-satellite DNA derivative revealed both DNA ends to be highly flexible, a feature important...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boopathi, Ramachandran, Danev, Radostin, Khoshouei, Maryam, Kale, Seyit, Nahata, Sunil, Ramos, Lorrie, Angelov, Dimitar, Dimitrov, Stefan, Hamiche, Ali, Petosa, Carlo, Bednar, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261176/ https://www.ncbi.nlm.nih.gov/pubmed/32313946 http://dx.doi.org/10.1093/nar/gkaa246

Ejemplares similares

Molecular Mechanism of Nucleosome Recognition by the Pioneer Transcription Factor Sox
por: Ozden, Burcu, et al.
Publicado: (2023)

Cryo-EM structure of haemoglobin at 3.2 Å determined with the Volta phase plate
por: Khoshouei, Maryam, et al.
Publicado: (2017)

Generation of Remosomes by the SWI/SNF Chromatin Remodeler Family
por: Shukla, Manu Shubhdarshan, et al.
Publicado: (2019)

Cryo-EM single particle analysis with the Volta phase plate
por: Danev, Radostin, et al.
Publicado: (2016)

Volta phase plate cryo-EM of the small protein complex Prx3
por: Khoshouei, Maryam, et al.
Publicado: (2016)

3.9 Å structure of the nucleosome core particle determined by phase-plate cryo-EM
por: Chua, Eugene Y.D., et al.
Publicado: (2016)

From crystal and NMR structures, footprints and cryo-electron-micrographs to large and soft structures: nanoscale modeling of the nucleosomal stem
por: Meyer, Sam, et al.
Publicado: (2011)

The cryo‐EM structure of the CENP‐A nucleosome in complex with ggKNL2
por: Jiang, Honghui, et al.
Publicado: (2023)

Improved applicability and robustness of fast cryo-electron tomography data acquisition
por: Eisenstein, Fabian, et al.
Publicado: (2019)

Using the Volta phase plate with defocus for cryo-EM single particle analysis
por: Danev, Radostin, et al.
Publicado: (2017)

Fast and accurate defocus modulation for improved tunability of cryo-EM experiments
por: Danev, Radostin, et al.
Publicado: (2020)

CENP-A nucleosome clusters form rosette-like structures around HJURP during G1
por: Andronov, Leonid, et al.
Publicado: (2019)

Stable complex formation of CENP-B with the CENP-A nucleosome
por: Fujita, Risa, et al.
Publicado: (2015)

The docking domain of histone H2A is required for H1 binding and RSC-mediated nucleosome remodeling
por: Shukla, Manu Shubhdarshan, et al.
Publicado: (2011)

Tracy-Widom distribution in AdS/CFT
por: Korchemsky, Gregory
Publicado: (2023)

Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment
por: Zhou, Bing-Rui, et al.
Publicado: (2019)

Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N
por: Carroll, Christopher W., et al.
Publicado: (2009)

Molecular basis of CENP-C association with the CENP-A nucleosome at yeast centromeres
por: Xiao, Hua, et al.
Publicado: (2017)

Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore
por: Tian, Tian, et al.
Publicado: (2018)

Decoding the centromeric nucleosome through CENP-N
por: Pentakota, Satyakrishna, et al.
Publicado: (2017)

Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle
por: Majumder, Parijat, et al.
Publicado: (2019)

Tracy-Widom GUE law and symplectic invariants
por: Borot, Gaetan, et al.
Publicado: (2010)

Widom Lines in Binary Mixtures of Supercritical Fluids
por: Raju, Muralikrishna, et al.
Publicado: (2017)

Supercritical water anomalies in the vicinity of the Widom line
por: Karalis, Konstantinos, et al.
Publicado: (2019)

On randomized sketching algorithms and the Tracy–Widom law
por: Ahfock, Daniel, et al.
Publicado: (2023)

The incorporation of the novel histone variant H2AL2 confers unusual structural and functional properties of the nucleosome
por: Syed, Sajad Hussain, et al.
Publicado: (2009)

Centromeric and ectopic assembly of CENP-A chromatin in health and cancer: old marks and new tracks
por: Sharma, Abhishek Bharadwaj, et al.
Publicado: (2019)

Routine sub-2.5 Å cryo-EM structure determination of GPCRs
por: Danev, Radostin, et al.
Publicado: (2021)

The Sequence Dependent Nanoscale Structure of CENP-A Nucleosomes
por: Stormberg, Tommy, et al.
Publicado: (2022)

Electrons receive individual treatment with electron-event representation
por: Danev, Radostin
Publicado: (2020)

RSC remodeling of oligo-nucleosomes: an atomic force microscopy study
por: Montel, Fabien, et al.
Publicado: (2011)

Binding of NF-κB to Nucleosomes: Effect of Translational Positioning, Nucleosome Remodeling and Linker Histone H1
por: Lone, Imtiaz Nisar, et al.
Publicado: (2013)

Phase-plate cryo-EM structure of a class B GPCR-G protein complex
por: Liang, Yi-Lynn, et al.
Publicado: (2017)

Dual recognition of CENP-A nucleosomes is required for centromere assembly
por: Carroll, Christopher W., et al.
Publicado: (2010)

Nap1 regulates proper CENP-B binding to nucleosomes
por: Tachiwana, Hiroaki, et al.
Publicado: (2013)

The octamer is the major form of CENP-A nucleosomes at human centromeres
por: Hasson, Dan, et al.
Publicado: (2013)

CENP-A confers a reduction in height on octameric nucleosomes
por: Miell, Matthew D. D., et al.
Publicado: (2013)

Nanoscale dynamics of centromere nucleosomes and the critical roles of CENP-A
por: Stumme-Diers, Micah P, et al.
Publicado: (2018)

Internal modifications in the CENP-A nucleosome modulate centromeric dynamics
por: Bui, Minh, et al.
Publicado: (2017)

CENP-C directs a structural transition of the CENP-A nucleosome mainly through sliding of DNA gyres
por: Falk, Samantha J., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1edplfmmnb1ii196as24uvoib9