Phage T7 DNA mimic protein Ocr is a potent inhibitor of BREX defence

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BREX (for BacteRiophage EXclusion) is a superfamily of common bacterial and archaeal defence systems active against diverse bacteriophages. While the mechanism of BREX defence is currently unknown, self versus non-self differentiation requires methylation of specific asymmetric sites in host DNA by...

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Detalles Bibliográficos
Autores principales: Isaev, Artem, Drobiazko, Alena, Sierro, Nicolas, Gordeeva, Julia, Yosef, Ido, Qimron, Udi, Ivanov, Nikolai V, Severinov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261183/
https://www.ncbi.nlm.nih.gov/pubmed/32338761
http://dx.doi.org/10.1093/nar/gkaa290
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