Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA

RNA decay is a key element of mitochondrial RNA metabolism. To date, the only well-documented machinery that plays a role in mtRNA decay in humans is the complex of polynucleotide phosphorylase (PNPase) and SUV3 helicase, forming the degradosome. REXO2, a homolog of prokaryotic oligoribonucleases pr...

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Detalles Bibliográficos
Autores principales: Szewczyk, Maciej, Malik, Deepshikha, Borowski, Lukasz S, Czarnomska, Sylwia D, Kotrys, Anna V, Klosowska-Kosicka, Kamila, Nowotny, Marcin, Szczesny, Roman J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261184/
https://www.ncbi.nlm.nih.gov/pubmed/32365187
http://dx.doi.org/10.1093/nar/gkaa302

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