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Uncovering the key dimensions of high-throughput biomolecular data using deep learning

Recent advances in high-throughput single-cell RNA-seq have enabled us to measure thousands of gene expression levels at single-cell resolution. However, the transcriptomic profiles are high-dimensional and sparse in nature. To address it, a deep learning framework based on auto-encoder, termed Deep...

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Detalles Bibliográficos
Autores principales: Zhang, Shixiong, Li, Xiangtao, Lin, Qiuzhen, Lin, Jiecong, Wong, Ka-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261195/
https://www.ncbi.nlm.nih.gov/pubmed/32232416
http://dx.doi.org/10.1093/nar/gkaa191