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High Concentrations of Uric Acid and Angiotensin II Act Additively to Produce Endothelial Injury

Renin angiotensin (Ang) system (RAS) activation in metabolic syndrome (MS) patients is associated with elevated uric acid (UA) levels, resulting in endothelial system dysfunction. Our previous study demonstrated that excessive UA could cause endothelial injury through the aldose reductase (AR) pathw...

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Detalles Bibliográficos
Autores principales: Hong, Quan, Wang, Liyuan, Huang, Zhiyong, Feng, Zhe, Cui, Shaoyuan, Fu, Bo, Cai, Guangyan, Chen, Xiangmei, Wu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261330/
https://www.ncbi.nlm.nih.gov/pubmed/32565731
http://dx.doi.org/10.1155/2020/8387654

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