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Review 1: Lung transplant—from donor selection to graft preparation

For various end-stage lung diseases, lung transplantation remains one of the only viable treatment options. While the demand for lung transplantation has steadily risen over the last few decades, the availability of donor grafts is limited, which have resulted in progressively longer waiting lists....

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Detalles Bibliográficos
Autores principales: Jin, Zhaosheng, Hana, Zac, Alam, Azeem, Rajalingam, Shamala, Abayalingam, Mayavan, Wang, Zhiping, Ma, Daqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261511/
https://www.ncbi.nlm.nih.gov/pubmed/32476043
http://dx.doi.org/10.1007/s00540-020-02800-z
Descripción
Sumario:For various end-stage lung diseases, lung transplantation remains one of the only viable treatment options. While the demand for lung transplantation has steadily risen over the last few decades, the availability of donor grafts is limited, which have resulted in progressively longer waiting lists. In the early years of lung transplantation, only the ‘ideal’ donor grafts are considered for transplantation. Due to the donor shortages, there is ongoing discussion about the safe use of ‘suboptimal’ grafts to expand the donor pool. In this review, we will discuss the considerations around donor selection, donor-recipient matching, graft preparation and graft optimisation.