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Pulmonary artery catheter use in acute myocardial infarction‐cardiogenic shock
AIMS: The aim of this study is to evaluate the contemporary use of a pulmonary artery catheter (PAC) in acute myocardial infarction‐cardiogenic shock (AMI‐CS). METHODS AND RESULTS: A retrospective cohort of AMI‐CS admissions using the National Inpatient Sample (2000–2014) was identified. Admissions...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261549/ https://www.ncbi.nlm.nih.gov/pubmed/32239806 http://dx.doi.org/10.1002/ehf2.12652 |
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author | Vallabhajosyula, Saraschandra Shankar, Aditi Patlolla, Sri Harsha Prasad, Abhiram Bell, Malcolm R. Jentzer, Jacob C. Arora, Shilpkumar Vallabhajosyula, Saarwaani Gersh, Bernard J. Jaffe, Allan S. Holmes, David R. Dunlay, Shannon M. Barsness, Gregory W. |
author_facet | Vallabhajosyula, Saraschandra Shankar, Aditi Patlolla, Sri Harsha Prasad, Abhiram Bell, Malcolm R. Jentzer, Jacob C. Arora, Shilpkumar Vallabhajosyula, Saarwaani Gersh, Bernard J. Jaffe, Allan S. Holmes, David R. Dunlay, Shannon M. Barsness, Gregory W. |
author_sort | Vallabhajosyula, Saraschandra |
collection | PubMed |
description | AIMS: The aim of this study is to evaluate the contemporary use of a pulmonary artery catheter (PAC) in acute myocardial infarction‐cardiogenic shock (AMI‐CS). METHODS AND RESULTS: A retrospective cohort of AMI‐CS admissions using the National Inpatient Sample (2000–2014) was identified. Admissions with concomitant cardiac surgery or non‐AMI aetiology for cardiogenic shock were excluded. The outcomes of interest were in‐hospital mortality, resource utilization, and temporal trends in cohorts with and without PAC use. In the non‐PAC cohort, the use and outcomes of right heart catheterization was evaluated. Multivariable regression and propensity matching was used to adjust for confounding. During 2000–2014, 364 001 admissions with AMI‐CS were included. PAC was used in 8.1% with a 75% decrease during over the study period (13.9% to 5.4%). Greater proportion of admissions to urban teaching hospitals received PACs (9.5%) compared with urban non‐teaching (7.1%) and rural hospitals (5.4%); P < 0.001. Younger age, male sex, white race, higher comorbidity, noncardiac organ failure, use of mechanical circulatory support, and noncardiac support were independent predictors of PAC use. The PAC cohort had higher in‐hospital mortality (adjusted odds ratio 1.07 [95% confidence interval 1.04–1.10]), longer length of stay (10.9 ± 10.9 vs. 8.2 ± 9.3 days), higher hospitalization costs ($128 247 ± 138 181 vs. $96 509 ± 116 060), and lesser discharges to home (36.3% vs. 46.4%) (all P < 0.001). In 6200 propensity‐matched pairs, in‐hospital mortality was comparable between the two cohorts (odds ratio 1.01 [95% confidence interval 0.94–1.08]). Right heart catheterization was used in 12.5% of non‐PAC admissions and was a marker of greater severity but did not indicate worse outcomes. CONCLUSIONS: In AMI‐CS, there was a 75% decrease in PAC use between 2000 and 2014. Admissions receiving a PAC were a higher risk cohort with worse clinical outcomes. |
format | Online Article Text |
id | pubmed-7261549 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72615492020-06-01 Pulmonary artery catheter use in acute myocardial infarction‐cardiogenic shock Vallabhajosyula, Saraschandra Shankar, Aditi Patlolla, Sri Harsha Prasad, Abhiram Bell, Malcolm R. Jentzer, Jacob C. Arora, Shilpkumar Vallabhajosyula, Saarwaani Gersh, Bernard J. Jaffe, Allan S. Holmes, David R. Dunlay, Shannon M. Barsness, Gregory W. ESC Heart Fail Original Research Articles AIMS: The aim of this study is to evaluate the contemporary use of a pulmonary artery catheter (PAC) in acute myocardial infarction‐cardiogenic shock (AMI‐CS). METHODS AND RESULTS: A retrospective cohort of AMI‐CS admissions using the National Inpatient Sample (2000–2014) was identified. Admissions with concomitant cardiac surgery or non‐AMI aetiology for cardiogenic shock were excluded. The outcomes of interest were in‐hospital mortality, resource utilization, and temporal trends in cohorts with and without PAC use. In the non‐PAC cohort, the use and outcomes of right heart catheterization was evaluated. Multivariable regression and propensity matching was used to adjust for confounding. During 2000–2014, 364 001 admissions with AMI‐CS were included. PAC was used in 8.1% with a 75% decrease during over the study period (13.9% to 5.4%). Greater proportion of admissions to urban teaching hospitals received PACs (9.5%) compared with urban non‐teaching (7.1%) and rural hospitals (5.4%); P < 0.001. Younger age, male sex, white race, higher comorbidity, noncardiac organ failure, use of mechanical circulatory support, and noncardiac support were independent predictors of PAC use. The PAC cohort had higher in‐hospital mortality (adjusted odds ratio 1.07 [95% confidence interval 1.04–1.10]), longer length of stay (10.9 ± 10.9 vs. 8.2 ± 9.3 days), higher hospitalization costs ($128 247 ± 138 181 vs. $96 509 ± 116 060), and lesser discharges to home (36.3% vs. 46.4%) (all P < 0.001). In 6200 propensity‐matched pairs, in‐hospital mortality was comparable between the two cohorts (odds ratio 1.01 [95% confidence interval 0.94–1.08]). Right heart catheterization was used in 12.5% of non‐PAC admissions and was a marker of greater severity but did not indicate worse outcomes. CONCLUSIONS: In AMI‐CS, there was a 75% decrease in PAC use between 2000 and 2014. Admissions receiving a PAC were a higher risk cohort with worse clinical outcomes. John Wiley and Sons Inc. 2020-04-02 /pmc/articles/PMC7261549/ /pubmed/32239806 http://dx.doi.org/10.1002/ehf2.12652 Text en © 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Research Articles Vallabhajosyula, Saraschandra Shankar, Aditi Patlolla, Sri Harsha Prasad, Abhiram Bell, Malcolm R. Jentzer, Jacob C. Arora, Shilpkumar Vallabhajosyula, Saarwaani Gersh, Bernard J. Jaffe, Allan S. Holmes, David R. Dunlay, Shannon M. Barsness, Gregory W. Pulmonary artery catheter use in acute myocardial infarction‐cardiogenic shock |
title | Pulmonary artery catheter use in acute myocardial infarction‐cardiogenic shock |
title_full | Pulmonary artery catheter use in acute myocardial infarction‐cardiogenic shock |
title_fullStr | Pulmonary artery catheter use in acute myocardial infarction‐cardiogenic shock |
title_full_unstemmed | Pulmonary artery catheter use in acute myocardial infarction‐cardiogenic shock |
title_short | Pulmonary artery catheter use in acute myocardial infarction‐cardiogenic shock |
title_sort | pulmonary artery catheter use in acute myocardial infarction‐cardiogenic shock |
topic | Original Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261549/ https://www.ncbi.nlm.nih.gov/pubmed/32239806 http://dx.doi.org/10.1002/ehf2.12652 |
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