Cargando…

Potential of Methylglyoxal-Conjugated Chitosan Nanoparticles in Treatment of Fluconazole-Resistant Candida albicans Infection in a Murine Model

BACKGROUND: Fungal infections are becoming more prevalent and threatening because of the continuous emergence of azole-resistant fungal infections. The present study was aimed to assess the activity of free Methylglyoxal (MG) or MG-conjugated chitosan nanoparticles (MGCN) against fluconazole-resista...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Shaheer Hasan, Younus, Hina, Allemailem, Khaled S, Almatroudi, Ahmad, Alrumaihi, Faris, Alruwetei, Abdulmohsen M, Alsahli, Mohammed A, Khan, Arif, Khan, Masood Alam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261666/ https://www.ncbi.nlm.nih.gov/pubmed/32547022 http://dx.doi.org/10.2147/IJN.S249625

Ejemplares similares

Encapsulation of MERS antigen into α-GalCer-bearing-liposomes elicits stronger effector and memory immune responses in immunocompetent and leukopenic mice
por: Khan, Masood Alam, et al.
Publicado: (2022)

Methanolic Fenugreek Seed Extract Induces p53-Dependent Mitotic Catastrophe in Breast Cancer Cells, Leading to Apoptosis
por: Alrumaihi, Faris A, et al.
Publicado: (2021)

Coadministration of Ginger Extract and Fluconazole Shows a Synergistic Effect in the Treatment of Drug-Resistant Vulvovaginal Candidiasis
por: Khan, Arif, et al.
Publicado: (2021)

Liposomal Ellagic Acid Alleviates Cyclophosphamide-Induced Toxicity and Eliminates the Systemic Cryptococcus neoformans Infection in Leukopenic Mice
por: Khan, Masood Alam, et al.
Publicado: (2021)

Safety and Therapeutic Efficacy of Thymoquinone-Loaded Liposomes against Drug-Sensitive and Drug-Resistant Acinetobacter baumannii
por: Allemailem, Khaled S., et al.
Publicado: (2021)

Therapeutic Effect of Bilsaan, Sambucus nigra Stem Exudate, on the OVA-Induced Allergic Asthma in Mice
por: Alrumaihi, Faris, et al.
Publicado: (2020)

Therapeutic potential of thymoquinone liposomes against the systemic infection of Candida albicans in diabetic mice
por: Khan, Masood A., et al.
Publicado: (2018)

Antimicrobial, Immunomodulatory and Anti-Inflammatory Potential of Liposomal Thymoquinone: Implications in the Treatment of Bacterial Pneumonia in Immunocompromised Mice
por: Allemailem, Khaled S., et al.
Publicado: (2021)

Fatty Acid Synthase (FASN) siRNA-Encapsulated-Her-2 Targeted Fab’-Immunoliposomes for Gene Silencing in Breast Cancer Cells
por: Khan, Arif, et al.
Publicado: (2020)

Diallyl Sulfide-Mediated Modulation of the Fatty Acid Synthase (FASN) Leads to Cancer Cell Death in BaP-Induced Lung Carcinogenesis in Swiss Mice
por: Khan, Arif, et al.
Publicado: (2020)

Synergistic Interactions of Eugenol-tosylate and Its Congeners with Fluconazole against Candida albicans
por: Ahmad, Aijaz, et al.
Publicado: (2015)

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management
por: Allemailem, Khaled S., et al.
Publicado: (2022)

Safety and Prophylactic Efficacy of Liposome-Based Vaccine against the Drug-Resistant Acinetobacter baumannii in Mice
por: Khan, Masood Alam, et al.
Publicado: (2022)

Glycosphingolipids (GSLs) from Sphingomonas paucimobilis Increase the Efficacy of Liposome-Based Nanovaccine against Acinetobacter baumannii-Associated Pneumonia in Immunocompetent and Immunocompromised Mice
por: Khan, Masood Alam, et al.
Publicado: (2022)

Synergistic Antifungal Activity of Chitosan with Fluconazole against Candida albicans, Candida tropicalis, and Fluconazole-Resistant Strains
por: Lo, Wei-Hsuan, et al.
Publicado: (2020)

Experimental and Theoretical Insights on Chemopreventive Effect of the Liposomal Thymoquinone Against Benzo[a]pyrene-Induced Lung Cancer in Swiss Albino Mice
por: Khan, Arif, et al.
Publicado: (2022)

Safety, Stability, and Therapeutic Efficacy of Long-Circulating TQ-Incorporated Liposomes: Implication in the Treatment of Lung Cancer
por: Khan, Arif, et al.
Publicado: (2022)

Lipid-Based Nanoparticle Formulation of Diallyl Trisulfide Chemosensitizes the Growth Inhibitory Activity of Doxorubicin in Colorectal Cancer Model: A Novel In Vitro, In Vivo and In Silico Analysis
por: Alrumaihi, Faris, et al.
Publicado: (2022)

The Effect of Liposomal Diallyl Disulfide and Oxaliplatin on Proliferation of Colorectal Cancer Cells: In Vitro and In Silico Analysis
por: Alrumaihi, Faris, et al.
Publicado: (2022)

Ambroxol Hydrochloride Combined with Fluconazole Reverses the Resistance of Candida albicans to Fluconazole
por: Li, Xiuyun, et al.
Publicado: (2017)

Fluconazole impacts the extracellular matrix of fluconazole-susceptible and -resistant Candida albicans and Candida glabrata biofilms
por: Panariello, Beatriz Helena Dias, et al.
Publicado: (2018)

Innovative Strategies of Reprogramming Immune System Cells by Targeting CRISPR/Cas9-Based Genome-Editing Tools: A New Era of Cancer Management
por: Allemailem, Khaled S, et al.
Publicado: (2023)

The Synergism of the Small Molecule ENOblock and Fluconazole Against Fluconazole-Resistant Candida albicans
por: Li, Liping, et al.
Publicado: (2019)

Identification and Characterization of Mediators of Fluconazole Tolerance in Candida albicans
por: Delarze, Eric, et al.
Publicado: (2020)

Liposome-Mediated Delivery of MERS Antigen Induces Potent Humoral and Cell-Mediated Immune Response in Mice
por: Khan, Masood Alam, et al.
Publicado: (2022)

Time-Kill Kinetics of Rezafungin (CD101) in Vagina-Simulative Medium for Fluconazole-Susceptible and Fluconazole-Resistant Candida albicans and Non-albicans Candida Species
por: Locke, Jeffrey B., et al.
Publicado: (2018)

Novel Approaches of Dysregulating Lysosome Functions in Cancer Cells by Specific Drugs and Its Nanoformulations: A Smart Approach of Modern Therapeutics
por: Allemailem, Khaled S, et al.
Publicado: (2021)

Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways
por: Rahmani, Arshad Husain, et al.
Publicado: (2023)

Effects and Mechanisms of Kaempferol in the Management of Cancers through Modulation of Inflammation and Signal Transduction Pathways
por: Almatroudi, Ahmad, et al.
Publicado: (2023)

Glutathione Metabolism in Candida albicans Resistant Strains to Fluconazole and Micafungin
por: Maras, Bruno, et al.
Publicado: (2014)

Biofilm Formation and Susceptibility to Amphotericin B and Fluconazole in Candida albicans
por: Zarei Mahmoudabadi, Ali, et al.
Publicado: (2014)

Susceptibility of Fluconazole-Resistant Candida albicans to Thyme Essential Oil
por: Alshaikh, Najla A, et al.
Publicado: (2021)

Mathematical Modeling of Fluconazole Resistance in the Ergosterol Pathway of Candida albicans
por: Yu, Paul K., et al.
Publicado: (2022)

Genome-wide translational response of Candida albicans to fluconazole treatment
por: Choudhary, Saket, et al.
Publicado: (2023)

Novel hydroxamates potentiated in vitro activity of fluconazole against Candida albicans
por: Paul-Satyaseela, Maneesh, et al.
Publicado: (2017)

Fluconazole resistance in Candida albicans is induced by Pseudomonas aeruginosa quorum sensing
por: Bandara, H. M. H. N., et al.
Publicado: (2020)

Copper Availability Influences the Transcriptomic Response of Candida albicans to Fluconazole Stress
por: Hunsaker, Elizabeth W, et al.
Publicado: (2021)

Biofilm Alterations on the Stepwise Acquisition of Fluconazole-resistant Candida Albicans Isolates
por: Song, Na-Na, et al.
Publicado: (2022)

Zerumbone Disturbs the Extracellular Matrix of Fluconazole-Resistant Candida albicans Biofilms
por: Abreu-Pereira, César Augusto, et al.
Publicado: (2023)

The Influence of Tea Tree Oil (Melaleuca alternifolia) on Fluconazole Activity against Fluconazole-Resistant Candida albicans Strains
por: Mertas, Anna, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4c1hpfph4to9oc43jmgtsja9ra