Heterozygous Genotype rs17580 AT (PiS) in SERPINA1 is Associated with COPD Secondary to Biomass-Burning and Tobacco Smoking: A Case–Control and Populational Study

PURPOSE: The protease inhibitor S (PiS) and Z (PiZ) variants have been stated as the only genetic cause of chronic obstructive pulmonary disease (COPD) in Caucasians. However, its frequency in admixed populations is low. We aimed to identify genetic susceptibility between PiS (rs17580) and PiZ (rs28...

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Detalles Bibliográficos
Autores principales: Pérez-Rubio, Gloria, Ambrocio-Ortiz, Enrique, López-Flores, Luis A, Juárez-Martín, Ana I, Jiménez-Valverde, Luis Octavio, Zoreque-Cabrera, Susana, Galicia-Negrete, Gustavo, Ramírez-Díaz, María Elena, Cruz-Vicente, Filiberto, Castillejos-López, Manuel de Jesús, Salinas-Lara, Citlaltepetl, Hernández-Zenteno, Rafael de Jesús, Ramírez-Venegas, Alejandra, Falfán-Valencia, Ramcés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261677/
https://www.ncbi.nlm.nih.gov/pubmed/32547005
http://dx.doi.org/10.2147/COPD.S247446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261677/
https://www.ncbi.nlm.nih.gov/pubmed/32547005
http://dx.doi.org/10.2147/COPD.S247446

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