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Vorinostat in the acute neuroinflammatory form of X‐linked adrenoleukodystrophy
OBJECTIVE: To identify a pharmacological compound targeting macrophages, the most affected immune cells in inflammatory X‐linked adrenoleukodystrophy (cerebral X‐ALD) caused by ABCD1 mutations and involved in the success of hematopoietic stem cell transplantation and gene therapy. METHODS: A compara...
Autores principales: | Zierfuss, Bettina, Weinhofer, Isabelle, Kühl, Jörn‐Sven, Köhler, Wolfgang, Bley, Annette, Zauner, Katharina, Binder, Johannes, Martinović, Ksenija, Seiser, Christian, Hertzberg, Christoph, Kemp, Stephan, Egger, Gerda, Leitner, Gerda, Bauer, Jan, Wiesinger, Christoph, Kunze, Markus, Forss‐Petter, Sonja, Berger, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261758/ https://www.ncbi.nlm.nih.gov/pubmed/32359032 http://dx.doi.org/10.1002/acn3.51015 |
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