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High-Dose Cyclophosphamide Administration Orchestrates Phenotypic and Functional Alterations of Immature Dendritic Cells and Regulates Th Cell Polarization

High-dose cyclophosphamide (CTX) inhibits the immune response. Dendritic cells (DCs) are professional antigen presenting cells (APCs) with a crucial role in initiating immune responses and sustaining immune tolerance. The relative contribution of DCs to immunosuppression induced by high-dose CTX is...

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Detalles Bibliográficos
Autores principales:	Bao, Lei, Hao, Changfu, Wang, Juan, Wang, Di, Zhao, Youliang, Li, Yiping, Yao, Wu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261842/ https://www.ncbi.nlm.nih.gov/pubmed/32523537 http://dx.doi.org/10.3389/fphar.2020.00775

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