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Shiga Toxin-Bearing Microvesicles Exert a Cytotoxic Effect on Recipient Cells Only When the Cells Express the Toxin Receptor
Shiga toxin is the main virulence factor of non-invasive enterohemorrhagic Escherichia coli strains capable of causing hemolytic uremic syndrome. Our group has previously shown that the toxin can reach the kidney within microvesicles where it is taken up by renal cells and the vesicles release their...
Autores principales: | Johansson, Karl, Willysson, Annie, Kristoffersson, Ann-Charlotte, Tontanahal, Ashmita, Gillet, Daniel, Ståhl, Anne-lie, Karpman, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261856/ https://www.ncbi.nlm.nih.gov/pubmed/32523894 http://dx.doi.org/10.3389/fcimb.2020.00212 |
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