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Pyrimethamine Elicits Antitumor Effects on Prostate Cancer by Inhibiting the p38-NF-κB Pathway

Since incurable castration-resistant prostate cancer (CRPC) inevitably develops following treatment with androgen deprivation therapy, there is an urgent need to devise new therapeutic strategies to treat this cancer. Pyrimethamine, an FDA-approved antimalarial drug, is known to exert an antitumor a...

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Detalles Bibliográficos
Autores principales:	Zhou, Xumin, Zhang, Jinming, Hu, Xiaoping, He, Peiqing, Guo, Jianyu, Li, Jun, Lan, Tian, Liu, Jumei, Peng, Lilan, Li, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261869/ https://www.ncbi.nlm.nih.gov/pubmed/32523533 http://dx.doi.org/10.3389/fphar.2020.00758

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