NADPH oxidases: Current aspects and tools

Reactive oxygen species (ROS) have been shown or at least suggested to play an essential role for cellular signaling as second messengers. NADPH oxidases represent a source of controlled ROS formation. Accordingly, understanding the role of individual NADPH oxidases bears potential to interfere with...

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Detalles Bibliográficos
Autor principal: Schröder, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Graphical Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262010/
https://www.ncbi.nlm.nih.gov/pubmed/32480354
http://dx.doi.org/10.1016/j.redox.2020.101512
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author Schröder, Katrin
author_facet Schröder, Katrin
author_sort Schröder, Katrin
collection PubMed
description Reactive oxygen species (ROS) have been shown or at least suggested to play an essential role for cellular signaling as second messengers. NADPH oxidases represent a source of controlled ROS formation. Accordingly, understanding the role of individual NADPH oxidases bears potential to interfere with intracellular signaling cascades without disturbing the signaling itself. Many tools have been developed to study or inhibit the functions and roles of the NADPH oxidases. This short review summarizes diseases, potentially associated with NADPH oxidases, genetically modified animals, and inhibitors.
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spelling pubmed-72620102020-06-01 NADPH oxidases: Current aspects and tools Schröder, Katrin Redox Biol Graphical Review Reactive oxygen species (ROS) have been shown or at least suggested to play an essential role for cellular signaling as second messengers. NADPH oxidases represent a source of controlled ROS formation. Accordingly, understanding the role of individual NADPH oxidases bears potential to interfere with intracellular signaling cascades without disturbing the signaling itself. Many tools have been developed to study or inhibit the functions and roles of the NADPH oxidases. This short review summarizes diseases, potentially associated with NADPH oxidases, genetically modified animals, and inhibitors. Elsevier 2020-05-23 /pmc/articles/PMC7262010/ /pubmed/32480354 http://dx.doi.org/10.1016/j.redox.2020.101512 Text en © 2020 The Author http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Graphical Review
Schröder, Katrin
NADPH oxidases: Current aspects and tools
title NADPH oxidases: Current aspects and tools
title_full NADPH oxidases: Current aspects and tools
title_fullStr NADPH oxidases: Current aspects and tools
title_full_unstemmed NADPH oxidases: Current aspects and tools
title_short NADPH oxidases: Current aspects and tools
title_sort nadph oxidases: current aspects and tools
topic Graphical Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262010/
https://www.ncbi.nlm.nih.gov/pubmed/32480354
http://dx.doi.org/10.1016/j.redox.2020.101512
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