Cellular Location of HNF4α is Linked With Terminal Liver Failure in Humans

Hepatocyte nuclear factor 4 alpha (HNF4α) is a transcription factor that plays a critical role in hepatocyte function, and HNF4α‐based reprogramming corrects terminal liver failure in rats with chronic liver disease. In the livers of patients with advanced cirrhosis, HNF4α RNA expression levels decr...

Descripción completa

Detalles Bibliográficos
Autores principales: Florentino, Rodrigo M., Fraunhoffer, Nicolas A., Morita, Kazutoyo, Takeishi, Kazuki, Ostrowska, Alina, Achreja, Abhinav, Animasahun, Olamide, Haep, Nils, Arazov, Shohrat, Agarwal, Nandini, Collin de l'Hortet, Alexandra, Guzman‐Lepe, Jorge, Tafaleng, Edgar N., Mukherjee, Amitava, Troy, Kris, Banerjee, Swati, Paranjpe, Shirish, Michalopoulos, George K., Bell, Aaron, Nagrath, Deepak, Hainer, Sarah J., Fox, Ira J., Soto‐Gutierrez, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262291/
https://www.ncbi.nlm.nih.gov/pubmed/32490322
http://dx.doi.org/10.1002/hep4.1505

Ejemplares similares

Ejemplares similares