Loss of c‐Jun N‐terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma

Targeted inhibition of the c‐Jun N‐terminal kinases (JNKs) has shown therapeutic potential in intrahepatic cholangiocarcinoma (CCA)‐related tumorigenesis. However, the cell‐type‐specific role and mechanisms triggered by JNK in liver parenchymal cells during CCA remain largely unknown. Here, we aimed...

Descripción completa

Detalles Bibliográficos
Autores principales: Cubero, Francisco Javier, Mohamed, Mohamed Ramadan, Woitok, Marius M., Zhao, Gang, Hatting, Maximilian, Nevzorova, Yulia A., Chen, Chaobo, Haybaeck, Johannes, de Bruin, Alain, Avila, Matias A., Boekschoten, Mark V., Davis, Roger J., Trautwein, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262317/
https://www.ncbi.nlm.nih.gov/pubmed/32490320
http://dx.doi.org/10.1002/hep4.1495

Ejemplares similares

Ejemplares similares