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Population dataset for 21 simple tandem repeat loci in the Akan population of Ghana
Short tandem repeat (STR) loci are widely used as genetic marker for ancestral and forensic analyses. The latter application includes for paternity testing and DNA profiling of samples collected from scenes of crime and suspects. This survey provides the first dataset for 21 STR loci across the Akan...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262416/ https://www.ncbi.nlm.nih.gov/pubmed/32490095 http://dx.doi.org/10.1016/j.dib.2020.105746 |
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author | Kofi, Abban Edward Hakim, Hashom Mohd Khan, Hussein Omar Ismail, Siti Afifah Ghansah, Anita Haslindawaty, Abd Rashid Nur Shamsuddin, Shaharum Aziz, Mohd Yusmaidie Chambers, Geoffrey Keith Edinur, Hisham Atan |
author_facet | Kofi, Abban Edward Hakim, Hashom Mohd Khan, Hussein Omar Ismail, Siti Afifah Ghansah, Anita Haslindawaty, Abd Rashid Nur Shamsuddin, Shaharum Aziz, Mohd Yusmaidie Chambers, Geoffrey Keith Edinur, Hisham Atan |
author_sort | Kofi, Abban Edward |
collection | PubMed |
description | Short tandem repeat (STR) loci are widely used as genetic marker for ancestral and forensic analyses. The latter application includes for paternity testing and DNA profiling of samples collected from scenes of crime and suspects. This survey provides the first dataset for 21 STR loci across the Akan population in Ghana by genotyping of 109 unrelated healthy individuals using Investigator 24plex kit. None of the STR loci screened deviated from Hardy-Weinberg equilibrium after applying Bonferroni correction. Overall, 224 unique alleles were observed with allele frequencies ranging from 0.005 to 0.518. The combined match probability, combined power of exclusion and combined power discrimination were 1 in 4.07 × 10(−25), 0.999999999 and 1, respectively. Principal coordinate analysis carried out using 21 STR allele frequency data mapped the Akans with Nigerian subpopulation groups (Hausa, Igbo and Yoruba), but separated from Thais of Thailand, Chechen of Jordan and Tijuana of Mexico. |
format | Online Article Text |
id | pubmed-7262416 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-72624162020-06-01 Population dataset for 21 simple tandem repeat loci in the Akan population of Ghana Kofi, Abban Edward Hakim, Hashom Mohd Khan, Hussein Omar Ismail, Siti Afifah Ghansah, Anita Haslindawaty, Abd Rashid Nur Shamsuddin, Shaharum Aziz, Mohd Yusmaidie Chambers, Geoffrey Keith Edinur, Hisham Atan Data Brief Genetics, Genomics and Molecular Biology Short tandem repeat (STR) loci are widely used as genetic marker for ancestral and forensic analyses. The latter application includes for paternity testing and DNA profiling of samples collected from scenes of crime and suspects. This survey provides the first dataset for 21 STR loci across the Akan population in Ghana by genotyping of 109 unrelated healthy individuals using Investigator 24plex kit. None of the STR loci screened deviated from Hardy-Weinberg equilibrium after applying Bonferroni correction. Overall, 224 unique alleles were observed with allele frequencies ranging from 0.005 to 0.518. The combined match probability, combined power of exclusion and combined power discrimination were 1 in 4.07 × 10(−25), 0.999999999 and 1, respectively. Principal coordinate analysis carried out using 21 STR allele frequency data mapped the Akans with Nigerian subpopulation groups (Hausa, Igbo and Yoruba), but separated from Thais of Thailand, Chechen of Jordan and Tijuana of Mexico. Elsevier 2020-05-22 /pmc/articles/PMC7262416/ /pubmed/32490095 http://dx.doi.org/10.1016/j.dib.2020.105746 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Genetics, Genomics and Molecular Biology Kofi, Abban Edward Hakim, Hashom Mohd Khan, Hussein Omar Ismail, Siti Afifah Ghansah, Anita Haslindawaty, Abd Rashid Nur Shamsuddin, Shaharum Aziz, Mohd Yusmaidie Chambers, Geoffrey Keith Edinur, Hisham Atan Population dataset for 21 simple tandem repeat loci in the Akan population of Ghana |
title | Population dataset for 21 simple tandem repeat loci in the Akan population of Ghana |
title_full | Population dataset for 21 simple tandem repeat loci in the Akan population of Ghana |
title_fullStr | Population dataset for 21 simple tandem repeat loci in the Akan population of Ghana |
title_full_unstemmed | Population dataset for 21 simple tandem repeat loci in the Akan population of Ghana |
title_short | Population dataset for 21 simple tandem repeat loci in the Akan population of Ghana |
title_sort | population dataset for 21 simple tandem repeat loci in the akan population of ghana |
topic | Genetics, Genomics and Molecular Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262416/ https://www.ncbi.nlm.nih.gov/pubmed/32490095 http://dx.doi.org/10.1016/j.dib.2020.105746 |
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