First clinical assessment of a prototype assay to detect the enzymatic activity of β-lactamase as a marker for pulmonary tuberculosis

The objective was to evaluate the sensitivity and specificity of a novel prototype test, TB REaD™, a reporter enzyme fluorescence–based assay, for pulmonary tuberculosis and to determine the optimal threshold for test positivity. This blinded, prospective study enrolled 250 patients, of which 23.2%...

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Detalles Bibliográficos
Autores principales: Nabeta, Pamela, Seshadri, Pratibha, Havumaki, Joshua, Mbhele, Silindile, Hendricks, Layla, Perkins, Mark D., Nicol, Mark P., Denkinger, Claudia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Biomedical 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262578/
https://www.ncbi.nlm.nih.gov/pubmed/32173144
http://dx.doi.org/10.1016/j.diagmicrobio.2020.115026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262578/
https://www.ncbi.nlm.nih.gov/pubmed/32173144
http://dx.doi.org/10.1016/j.diagmicrobio.2020.115026

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