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Pathway-Level Information ExtractoR (PLIER) for gene expression data
A major challenge in gene expression analysis is to accurately infer relevant biological insight, such as variation in cell type proportion or pathway activity, from global gene expression studies. We present a general solution for this problem that outperforms available cell proportion inference al...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262669/ https://www.ncbi.nlm.nih.gov/pubmed/31249421 http://dx.doi.org/10.1038/s41592-019-0456-1 |