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The future of stenting in patients with type A aortic dissection: a systematic review

Acute type A aortic dissection (ATAAD) carries high morbidity and mortality rates and is a clinical emergency. The reported mortality rate is 50% to 65% within the first 48 hours without surgical intervention. Open surgery therefore remains the gold standard management for ATAAD. However, in patient...

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Autores principales: Harky, Amer, Chan, Jeremy, MacCarthy-Ofosu, Beverly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262859/
https://www.ncbi.nlm.nih.gov/pubmed/31510840
http://dx.doi.org/10.1177/0300060519871372
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author Harky, Amer
Chan, Jeremy
MacCarthy-Ofosu, Beverly
author_facet Harky, Amer
Chan, Jeremy
MacCarthy-Ofosu, Beverly
author_sort Harky, Amer
collection PubMed
description Acute type A aortic dissection (ATAAD) carries high morbidity and mortality rates and is a clinical emergency. The reported mortality rate is 50% to 65% within the first 48 hours without surgical intervention. Open surgery therefore remains the gold standard management for ATAAD. However, in patients who are deemed unfit for surgery and where possible, endovascular repair offers a useful alternative to medical treatment alone or high-risk open surgical repair. Several case reports, case series, and retrospective studies have reported good outcomes following endovascular treatment. The endovascular option also has comparable early and late outcomes, favourable aortic remodelling, and satisfactory overall survival despite having a higher-risk patient cohort. However, stenting in patients with ATAAD undoubtedly still has several limitations and technical challenges.
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spelling pubmed-72628592020-06-10 The future of stenting in patients with type A aortic dissection: a systematic review Harky, Amer Chan, Jeremy MacCarthy-Ofosu, Beverly J Int Med Res Special Issue: Current Trends in Open and Endovascular Approach to Thoracic Aortic Diseases Acute type A aortic dissection (ATAAD) carries high morbidity and mortality rates and is a clinical emergency. The reported mortality rate is 50% to 65% within the first 48 hours without surgical intervention. Open surgery therefore remains the gold standard management for ATAAD. However, in patients who are deemed unfit for surgery and where possible, endovascular repair offers a useful alternative to medical treatment alone or high-risk open surgical repair. Several case reports, case series, and retrospective studies have reported good outcomes following endovascular treatment. The endovascular option also has comparable early and late outcomes, favourable aortic remodelling, and satisfactory overall survival despite having a higher-risk patient cohort. However, stenting in patients with ATAAD undoubtedly still has several limitations and technical challenges. SAGE Publications 2019-09-12 /pmc/articles/PMC7262859/ /pubmed/31510840 http://dx.doi.org/10.1177/0300060519871372 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Special Issue: Current Trends in Open and Endovascular Approach to Thoracic Aortic Diseases
Harky, Amer
Chan, Jeremy
MacCarthy-Ofosu, Beverly
The future of stenting in patients with type A aortic dissection: a systematic review
title The future of stenting in patients with type A aortic dissection: a systematic review
title_full The future of stenting in patients with type A aortic dissection: a systematic review
title_fullStr The future of stenting in patients with type A aortic dissection: a systematic review
title_full_unstemmed The future of stenting in patients with type A aortic dissection: a systematic review
title_short The future of stenting in patients with type A aortic dissection: a systematic review
title_sort future of stenting in patients with type a aortic dissection: a systematic review
topic Special Issue: Current Trends in Open and Endovascular Approach to Thoracic Aortic Diseases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262859/
https://www.ncbi.nlm.nih.gov/pubmed/31510840
http://dx.doi.org/10.1177/0300060519871372
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