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CD279 mediates the homeostasis and survival of regulatory T cells by enhancing T cell and macrophage interactions
CD279 is a cell surface protein predominantly expressed on T cells. Its ligands CD273 and CD274 are expressed on antigen‐presenting cells and tumors. CD279 has been shown to act as an important immune check point by inhibiting CD8 T cell activation, and antibodies against CD279 enhance T cell‐mediat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262947/ https://www.ncbi.nlm.nih.gov/pubmed/32324337 http://dx.doi.org/10.1002/2211-5463.12865 |