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Albuterol-Induced Type B Lactic Acidosis: Not an Uncommon Finding

Lactic acidosis (LA) is usually a medical emergency diagnosed by laboratory evaluation in emergency rooms (ERs) and hospital settings in critically ill patients. LA is classified into two major types based on pathophysiology; type A results from tissue hypoxia and/or hypoperfusion and type B results...

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Autores principales: Meegada, Sreenath, Muppidi, Vijayadershan, Siddamreddy, Suman, Challa, Tejo, Katta, Shravan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263006/
https://www.ncbi.nlm.nih.gov/pubmed/32494543
http://dx.doi.org/10.7759/cureus.8269
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author Meegada, Sreenath
Muppidi, Vijayadershan
Siddamreddy, Suman
Challa, Tejo
Katta, Shravan K
author_facet Meegada, Sreenath
Muppidi, Vijayadershan
Siddamreddy, Suman
Challa, Tejo
Katta, Shravan K
author_sort Meegada, Sreenath
collection PubMed
description Lactic acidosis (LA) is usually a medical emergency diagnosed by laboratory evaluation in emergency rooms (ERs) and hospital settings in critically ill patients. LA is classified into two major types based on pathophysiology; type A results from tissue hypoxia and/or hypoperfusion and type B results from deranged metabolic activity in the cells in the absence of hypoxia/hypoperfusion. Prompt evaluation and treatment are essential to prevent morbidity and mortality, especially in patients with type A LA. Most cases of LA are due to type A (hypoperfusion/hypoxia). However, with increased testing of lactic acid levels in ERs and hospitals, we are encountering a few cases of type B LA as well. Diagnosing the exact type is crucial because of differences in management. We here describe a patient with albuterol-induced type B LA, which resolved after discontinuing the albuterol breathing treatments.
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spelling pubmed-72630062020-06-02 Albuterol-Induced Type B Lactic Acidosis: Not an Uncommon Finding Meegada, Sreenath Muppidi, Vijayadershan Siddamreddy, Suman Challa, Tejo Katta, Shravan K Cureus Internal Medicine Lactic acidosis (LA) is usually a medical emergency diagnosed by laboratory evaluation in emergency rooms (ERs) and hospital settings in critically ill patients. LA is classified into two major types based on pathophysiology; type A results from tissue hypoxia and/or hypoperfusion and type B results from deranged metabolic activity in the cells in the absence of hypoxia/hypoperfusion. Prompt evaluation and treatment are essential to prevent morbidity and mortality, especially in patients with type A LA. Most cases of LA are due to type A (hypoperfusion/hypoxia). However, with increased testing of lactic acid levels in ERs and hospitals, we are encountering a few cases of type B LA as well. Diagnosing the exact type is crucial because of differences in management. We here describe a patient with albuterol-induced type B LA, which resolved after discontinuing the albuterol breathing treatments. Cureus 2020-05-25 /pmc/articles/PMC7263006/ /pubmed/32494543 http://dx.doi.org/10.7759/cureus.8269 Text en Copyright © 2020, Meegada et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Meegada, Sreenath
Muppidi, Vijayadershan
Siddamreddy, Suman
Challa, Tejo
Katta, Shravan K
Albuterol-Induced Type B Lactic Acidosis: Not an Uncommon Finding
title Albuterol-Induced Type B Lactic Acidosis: Not an Uncommon Finding
title_full Albuterol-Induced Type B Lactic Acidosis: Not an Uncommon Finding
title_fullStr Albuterol-Induced Type B Lactic Acidosis: Not an Uncommon Finding
title_full_unstemmed Albuterol-Induced Type B Lactic Acidosis: Not an Uncommon Finding
title_short Albuterol-Induced Type B Lactic Acidosis: Not an Uncommon Finding
title_sort albuterol-induced type b lactic acidosis: not an uncommon finding
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263006/
https://www.ncbi.nlm.nih.gov/pubmed/32494543
http://dx.doi.org/10.7759/cureus.8269
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