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Mitochondrial Quality Control and Cellular Proteostasis: Two Sides of the Same Coin
Mitochondrial dysfunction is a hallmark of cardiac pathophysiology. Defects in mitochondrial performance disrupt contractile function, overwhelm myocytes with reactive oxygen species (ROS), and transform these cellular powerhouses into pro-death organelles. Thus, quality control (QC) pathways aimed...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263099/ https://www.ncbi.nlm.nih.gov/pubmed/32528313 http://dx.doi.org/10.3389/fphys.2020.00515 |