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Progress toward understanding chromosome silencing by Xist RNA

The X inactive-specific transcript (Xist) gene is the master regulator of X chromosome inactivation in mammals. Xist produces a long noncoding (lnc)RNA that accumulates over the entire length of the chromosome from which it is transcribed, recruiting factors to modify underlying chromatin and silenc...

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Detalles Bibliográficos
Autores principales:	Brockdorff, Neil, Bowness, Joseph S., Wei, Guifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263139/ https://www.ncbi.nlm.nih.gov/pubmed/32482714 http://dx.doi.org/10.1101/gad.337196.120

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