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Molecular structures and mechanisms of DNA break processing in mouse meiosis

Exonucleolytic resection, critical to repair double-strand breaks (DSBs) by recombination, is not well understood, particularly in mammalian meiosis. Here, we define structures of resected DSBs in mouse spermatocytes genome-wide at nucleotide resolution. Resection tracts averaged 1100 nt, but with s...

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Detalles Bibliográficos
Autores principales:	Yamada, Shintaro, Hinch, Anjali Gupta, Kamido, Hisashi, Zhang, Yongwei, Edelmann, Winfried, Keeney, Scott
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263140/ https://www.ncbi.nlm.nih.gov/pubmed/32354835 http://dx.doi.org/10.1101/gad.336032.119

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