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Intragenic repeat expansion in the cell wall protein gene HPF1 controls yeast chronological aging

Aging varies among individuals due to both genetics and environment, but the underlying molecular mechanisms remain largely unknown. Using a highly recombined Saccharomyces cerevisiae population, we found 30 distinct quantitative trait loci (QTLs) that control chronological life span (CLS) in calori...

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Detalles Bibliográficos
Autores principales:	Barré, Benjamin P., Hallin, Johan, Yue, Jia-Xing, Persson, Karl, Mikhalev, Ekaterina, Irizar, Agurtzane, Holt, Sylvester, Thompson, Dawn, Molin, Mikael, Warringer, Jonas, Liti, Gianni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263189/ https://www.ncbi.nlm.nih.gov/pubmed/32277013 http://dx.doi.org/10.1101/gr.253351.119

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