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Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a clinicopathological condition characterized clinically by symptoms of esophageal dysfunction, with typical endoscopic findings and intra-epithelial eosinophilia on biopsy. This case report focuses on the historical aspect of EoE, clinical manifestations, and corre...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263406/ https://www.ncbi.nlm.nih.gov/pubmed/32494513 http://dx.doi.org/10.7759/cureus.7898 |
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author | Deepika, Keerti Adhikari, Ramesh Adapa, Sreedhar Naramala, Srikanth Konala, Venu Madhav |
author_facet | Deepika, Keerti Adhikari, Ramesh Adapa, Sreedhar Naramala, Srikanth Konala, Venu Madhav |
author_sort | Deepika, Keerti |
collection | PubMed |
description | Eosinophilic esophagitis (EoE) is a clinicopathological condition characterized clinically by symptoms of esophageal dysfunction, with typical endoscopic findings and intra-epithelial eosinophilia on biopsy. This case report focuses on the historical aspect of EoE, clinical manifestations, and correlation with immune disorders, medical management, and interventional management of EoE. We present a 20-year-old patient presenting with tightness in throat and odynophagia after the ingestion of certain foods. These symptoms resolve in two or three hours. Endoscopic examination of the upper gastrointestinal tract visualizes esophageal stenosis, and histological examination of the biopsy specimen reveals increased eosinophils in the esophageal mucosa. The patient was treated with fluticasone inhaler and has shown improvement in symptoms. EoE is a chronic esophageal disorder that is increasing in incidence and prevalence in both pediatric and adult age groups. This case report accentuates the complications of EoE, and delays in diagnosis lead to strictures, and fibro-stenotic disease and punctual recognition can govern the course of the disease. |
format | Online Article Text |
id | pubmed-7263406 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-72634062020-06-02 Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis Deepika, Keerti Adhikari, Ramesh Adapa, Sreedhar Naramala, Srikanth Konala, Venu Madhav Cureus Internal Medicine Eosinophilic esophagitis (EoE) is a clinicopathological condition characterized clinically by symptoms of esophageal dysfunction, with typical endoscopic findings and intra-epithelial eosinophilia on biopsy. This case report focuses on the historical aspect of EoE, clinical manifestations, and correlation with immune disorders, medical management, and interventional management of EoE. We present a 20-year-old patient presenting with tightness in throat and odynophagia after the ingestion of certain foods. These symptoms resolve in two or three hours. Endoscopic examination of the upper gastrointestinal tract visualizes esophageal stenosis, and histological examination of the biopsy specimen reveals increased eosinophils in the esophageal mucosa. The patient was treated with fluticasone inhaler and has shown improvement in symptoms. EoE is a chronic esophageal disorder that is increasing in incidence and prevalence in both pediatric and adult age groups. This case report accentuates the complications of EoE, and delays in diagnosis lead to strictures, and fibro-stenotic disease and punctual recognition can govern the course of the disease. Cureus 2020-04-30 /pmc/articles/PMC7263406/ /pubmed/32494513 http://dx.doi.org/10.7759/cureus.7898 Text en Copyright © 2020, Deepika et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Deepika, Keerti Adhikari, Ramesh Adapa, Sreedhar Naramala, Srikanth Konala, Venu Madhav Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis |
title | Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis |
title_full | Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis |
title_fullStr | Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis |
title_full_unstemmed | Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis |
title_short | Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis |
title_sort | dysphagia as an initial manifestation of eosinophilic esophagitis |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263406/ https://www.ncbi.nlm.nih.gov/pubmed/32494513 http://dx.doi.org/10.7759/cureus.7898 |
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