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Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis

Eosinophilic esophagitis (EoE) is a clinicopathological condition characterized clinically by symptoms of esophageal dysfunction, with typical endoscopic findings and intra-epithelial eosinophilia on biopsy. This case report focuses on the historical aspect of EoE, clinical manifestations, and corre...

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Autores principales: Deepika, Keerti, Adhikari, Ramesh, Adapa, Sreedhar, Naramala, Srikanth, Konala, Venu Madhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263406/
https://www.ncbi.nlm.nih.gov/pubmed/32494513
http://dx.doi.org/10.7759/cureus.7898
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author Deepika, Keerti
Adhikari, Ramesh
Adapa, Sreedhar
Naramala, Srikanth
Konala, Venu Madhav
author_facet Deepika, Keerti
Adhikari, Ramesh
Adapa, Sreedhar
Naramala, Srikanth
Konala, Venu Madhav
author_sort Deepika, Keerti
collection PubMed
description Eosinophilic esophagitis (EoE) is a clinicopathological condition characterized clinically by symptoms of esophageal dysfunction, with typical endoscopic findings and intra-epithelial eosinophilia on biopsy. This case report focuses on the historical aspect of EoE, clinical manifestations, and correlation with immune disorders, medical management, and interventional management of EoE. We present a 20-year-old patient presenting with tightness in throat and odynophagia after the ingestion of certain foods. These symptoms resolve in two or three hours. Endoscopic examination of the upper gastrointestinal tract visualizes esophageal stenosis, and histological examination of the biopsy specimen reveals increased eosinophils in the esophageal mucosa. The patient was treated with fluticasone inhaler and has shown improvement in symptoms. EoE is a chronic esophageal disorder that is increasing in incidence and prevalence in both pediatric and adult age groups. This case report accentuates the complications of EoE, and delays in diagnosis lead to strictures, and fibro-stenotic disease and punctual recognition can govern the course of the disease.
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spelling pubmed-72634062020-06-02 Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis Deepika, Keerti Adhikari, Ramesh Adapa, Sreedhar Naramala, Srikanth Konala, Venu Madhav Cureus Internal Medicine Eosinophilic esophagitis (EoE) is a clinicopathological condition characterized clinically by symptoms of esophageal dysfunction, with typical endoscopic findings and intra-epithelial eosinophilia on biopsy. This case report focuses on the historical aspect of EoE, clinical manifestations, and correlation with immune disorders, medical management, and interventional management of EoE. We present a 20-year-old patient presenting with tightness in throat and odynophagia after the ingestion of certain foods. These symptoms resolve in two or three hours. Endoscopic examination of the upper gastrointestinal tract visualizes esophageal stenosis, and histological examination of the biopsy specimen reveals increased eosinophils in the esophageal mucosa. The patient was treated with fluticasone inhaler and has shown improvement in symptoms. EoE is a chronic esophageal disorder that is increasing in incidence and prevalence in both pediatric and adult age groups. This case report accentuates the complications of EoE, and delays in diagnosis lead to strictures, and fibro-stenotic disease and punctual recognition can govern the course of the disease. Cureus 2020-04-30 /pmc/articles/PMC7263406/ /pubmed/32494513 http://dx.doi.org/10.7759/cureus.7898 Text en Copyright © 2020, Deepika et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Deepika, Keerti
Adhikari, Ramesh
Adapa, Sreedhar
Naramala, Srikanth
Konala, Venu Madhav
Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis
title Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis
title_full Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis
title_fullStr Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis
title_full_unstemmed Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis
title_short Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis
title_sort dysphagia as an initial manifestation of eosinophilic esophagitis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263406/
https://www.ncbi.nlm.nih.gov/pubmed/32494513
http://dx.doi.org/10.7759/cureus.7898
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