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Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2

The coronavirus known as SARS-CoV-2, which causes COVID-19 disease, is presently responsible for a global pandemic wherein more than 3.5 million people have been infected and more than 250,000 killed to-date. There is currently no vaccine for COVID-19, leaving governments and public health agencies...

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Autores principales: Mantlo, Emily, Evans, Alex, Patterson-Fortin, Laura, Boutros, Jenny, Smith, Richard, Paessler, Slobodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263491/
https://www.ncbi.nlm.nih.gov/pubmed/32511363
http://dx.doi.org/10.1101/2020.05.08.082701
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author Mantlo, Emily
Evans, Alex
Patterson-Fortin, Laura
Boutros, Jenny
Smith, Richard
Paessler, Slobodan
author_facet Mantlo, Emily
Evans, Alex
Patterson-Fortin, Laura
Boutros, Jenny
Smith, Richard
Paessler, Slobodan
author_sort Mantlo, Emily
collection PubMed
description The coronavirus known as SARS-CoV-2, which causes COVID-19 disease, is presently responsible for a global pandemic wherein more than 3.5 million people have been infected and more than 250,000 killed to-date. There is currently no vaccine for COVID-19, leaving governments and public health agencies with little defense against the virus aside from advising or enforcing best practices for virus transmission prevention, which include hand-washing, physical distancing, use of face covers, and use of effective disinfectants. In this study, a novel iodine complex called CupriDyne® was assessed for its ability to inactivate SARS-CoV-2. CupriDyne was shown to be effective in inactivating the virus in a time-dependent manner, reducing virus titers by 99% (2 logs) after 30 minutes, and reducing virus titers to below the detection limit after 60 minutes. The novel iodine complex tested herein offers a safe and gentle alternative to conventional disinfectants for use on indoor and outdoor surfaces.
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spelling pubmed-72634912020-06-07 Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2 Mantlo, Emily Evans, Alex Patterson-Fortin, Laura Boutros, Jenny Smith, Richard Paessler, Slobodan bioRxiv Article The coronavirus known as SARS-CoV-2, which causes COVID-19 disease, is presently responsible for a global pandemic wherein more than 3.5 million people have been infected and more than 250,000 killed to-date. There is currently no vaccine for COVID-19, leaving governments and public health agencies with little defense against the virus aside from advising or enforcing best practices for virus transmission prevention, which include hand-washing, physical distancing, use of face covers, and use of effective disinfectants. In this study, a novel iodine complex called CupriDyne® was assessed for its ability to inactivate SARS-CoV-2. CupriDyne was shown to be effective in inactivating the virus in a time-dependent manner, reducing virus titers by 99% (2 logs) after 30 minutes, and reducing virus titers to below the detection limit after 60 minutes. The novel iodine complex tested herein offers a safe and gentle alternative to conventional disinfectants for use on indoor and outdoor surfaces. Cold Spring Harbor Laboratory 2020-05-08 /pmc/articles/PMC7263491/ /pubmed/32511363 http://dx.doi.org/10.1101/2020.05.08.082701 Text en https://creativecommons.org/licenses/by-nd/4.0/This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nd/4.0/) , which allows reusers to copy and distribute the material in any medium or format in unadapted form only, and only so long as attribution is given to the creator. The license allows for commercial use.
spellingShingle Article
Mantlo, Emily
Evans, Alex
Patterson-Fortin, Laura
Boutros, Jenny
Smith, Richard
Paessler, Slobodan
Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2
title Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2
title_full Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2
title_fullStr Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2
title_full_unstemmed Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2
title_short Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2
title_sort efficacy of a novel iodine complex solution, cupridyne, in inactivating sars-cov-2
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263491/
https://www.ncbi.nlm.nih.gov/pubmed/32511363
http://dx.doi.org/10.1101/2020.05.08.082701
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