Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with COVID-19 Treated with Hydroxychloroquine

Novel coronavirus disease (COVID-19) is a highly contagious disease caused by severe acute respiratory distress syndrome coronavirus-2 that has resulted in the current global pandemic. Currently, there is no available treatment proven to be effective against COVID-19, but multiple medications, inclu...

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Autores principales: Asli, Rosmonaliza, Abdullah, Muhammad Syafiq, Chong, Pui Lin, Metussin, Dhiya, Momin, Riamiza Natalie, Mani, Babu Ivan, Chong, Vui Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263524/
https://www.ncbi.nlm.nih.gov/pubmed/32383430
http://dx.doi.org/10.4269/ajtmh.20-0376
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author Asli, Rosmonaliza
Abdullah, Muhammad Syafiq
Chong, Pui Lin
Metussin, Dhiya
Momin, Riamiza Natalie
Mani, Babu Ivan
Chong, Vui Heng
author_facet Asli, Rosmonaliza
Abdullah, Muhammad Syafiq
Chong, Pui Lin
Metussin, Dhiya
Momin, Riamiza Natalie
Mani, Babu Ivan
Chong, Vui Heng
author_sort Asli, Rosmonaliza
collection PubMed
description Novel coronavirus disease (COVID-19) is a highly contagious disease caused by severe acute respiratory distress syndrome coronavirus-2 that has resulted in the current global pandemic. Currently, there is no available treatment proven to be effective against COVID-19, but multiple medications, including hydroxychloroquine (HCQ), are used off label. We report the case of a 60-year-old woman without any cardiac history who developed right bundle brunch block and critically prolonged corrected electrocardiographic QT interval (QTc 631 ms) after treatment for 3 days with HCQ, which resolved on discontinuation of the medication. This case highlights a significant and potentially life-threatening complication of HCQ use.
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spelling pubmed-72635242020-06-03 Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with COVID-19 Treated with Hydroxychloroquine Asli, Rosmonaliza Abdullah, Muhammad Syafiq Chong, Pui Lin Metussin, Dhiya Momin, Riamiza Natalie Mani, Babu Ivan Chong, Vui Heng Am J Trop Med Hyg Articles Novel coronavirus disease (COVID-19) is a highly contagious disease caused by severe acute respiratory distress syndrome coronavirus-2 that has resulted in the current global pandemic. Currently, there is no available treatment proven to be effective against COVID-19, but multiple medications, including hydroxychloroquine (HCQ), are used off label. We report the case of a 60-year-old woman without any cardiac history who developed right bundle brunch block and critically prolonged corrected electrocardiographic QT interval (QTc 631 ms) after treatment for 3 days with HCQ, which resolved on discontinuation of the medication. This case highlights a significant and potentially life-threatening complication of HCQ use. The American Society of Tropical Medicine and Hygiene 2020-07 2020-05-07 /pmc/articles/PMC7263524/ /pubmed/32383430 http://dx.doi.org/10.4269/ajtmh.20-0376 Text en © The American Society of Tropical Medicine and Hygiene This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Articles
Asli, Rosmonaliza
Abdullah, Muhammad Syafiq
Chong, Pui Lin
Metussin, Dhiya
Momin, Riamiza Natalie
Mani, Babu Ivan
Chong, Vui Heng
Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with COVID-19 Treated with Hydroxychloroquine
title Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with COVID-19 Treated with Hydroxychloroquine
title_full Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with COVID-19 Treated with Hydroxychloroquine
title_fullStr Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with COVID-19 Treated with Hydroxychloroquine
title_full_unstemmed Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with COVID-19 Treated with Hydroxychloroquine
title_short Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with COVID-19 Treated with Hydroxychloroquine
title_sort case report: right bundle brunch block and qtc prolongation in a patient with covid-19 treated with hydroxychloroquine
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263524/
https://www.ncbi.nlm.nih.gov/pubmed/32383430
http://dx.doi.org/10.4269/ajtmh.20-0376
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