Cargando…
Particulate air pollution exposure during pregnancy and postpartum depression symptoms in women in Mexico City
BACKGROUND: Postpartum depression (PPD), which affects up to 1 in 5 mothers globally, negatively impacts the health of both mothers and children. Exposure to ambient air pollution has been linked to depressive symptoms in animal models and human studies, but the relationship between air pollution an...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263529/ https://www.ncbi.nlm.nih.gov/pubmed/31760258 http://dx.doi.org/10.1016/j.envint.2019.105325 |
_version_ | 1783540811504287744 |
---|---|
author | Niedzwiecki, Megan M. Rosa, Maria José Solano-González, Maritsa Kloog, Itai Just, Allan C. Martínez-Medina, Sandra Schnaas, Lourdes Tamayo-Ortiz, Marcela Wright, Robert O. Téllez-Rojo, Martha M. Wright, Rosalind J. |
author_facet | Niedzwiecki, Megan M. Rosa, Maria José Solano-González, Maritsa Kloog, Itai Just, Allan C. Martínez-Medina, Sandra Schnaas, Lourdes Tamayo-Ortiz, Marcela Wright, Robert O. Téllez-Rojo, Martha M. Wright, Rosalind J. |
author_sort | Niedzwiecki, Megan M. |
collection | PubMed |
description | BACKGROUND: Postpartum depression (PPD), which affects up to 1 in 5 mothers globally, negatively impacts the health of both mothers and children. Exposure to ambient air pollution has been linked to depressive symptoms in animal models and human studies, but the relationship between air pollution and PPD has not been widely studied. METHODS: In a birth cohort in Mexico City (509 mothers with available data), we examined the association between exposure to particulate matter ≤2.5 μm in diameter (PM(2.5)) with symptoms of psychological dysfunction at 1 and 6 months postpartum. Daily PM(2.5) estimates were derived from a hybrid satellite-based spatio-temporally resolved model and averaged over pregnancy and the first year postpartum. Edinburgh Postnatal Depression Scale (EPDS) scores at 1 and 6 months were used to assess the relationship between PM(2.5) exposure and probable PPD (EPDS score ≥13) using relative risk regression and symptoms of anhedonia, depression, and anxiety (derived from EPDS subscales) using negative binomial regression. RESULTS: A 5-μg/m(3) increase in average PM(2.5) exposure during pregnancy was associated with an increased risk of PPD at 6 months (RR = 1.59; 95% CI: 1.11 to 2.28) and of late-onset PPD (no PPD at 1 month, PPD at 6 months) (RR = 2.58; 95% CI: 1.40 to 4.73) in covariate-adjusted models. No association was observed between PM(2.5) exposure in the first year postpartum and PPD. Average PM(2.5) exposure during pregnancy was also associated with increased 6-month EPDS subscale symptom scores for anhedonia (p = 0.03) and depression (p = 0.04). CONCLUSION: Our results suggest that in women in Mexico City, particulate matter exposure during pregnancy is positively associated with PPD and symptoms of anhedonia and depression at 6 months postpartum. Future studies should examine mechanisms linking air pollution and other environmental exposures during pregnancy with postpartum psychological functioning. |
format | Online Article Text |
id | pubmed-7263529 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
record_format | MEDLINE/PubMed |
spelling | pubmed-72635292020-06-01 Particulate air pollution exposure during pregnancy and postpartum depression symptoms in women in Mexico City Niedzwiecki, Megan M. Rosa, Maria José Solano-González, Maritsa Kloog, Itai Just, Allan C. Martínez-Medina, Sandra Schnaas, Lourdes Tamayo-Ortiz, Marcela Wright, Robert O. Téllez-Rojo, Martha M. Wright, Rosalind J. Environ Int Article BACKGROUND: Postpartum depression (PPD), which affects up to 1 in 5 mothers globally, negatively impacts the health of both mothers and children. Exposure to ambient air pollution has been linked to depressive symptoms in animal models and human studies, but the relationship between air pollution and PPD has not been widely studied. METHODS: In a birth cohort in Mexico City (509 mothers with available data), we examined the association between exposure to particulate matter ≤2.5 μm in diameter (PM(2.5)) with symptoms of psychological dysfunction at 1 and 6 months postpartum. Daily PM(2.5) estimates were derived from a hybrid satellite-based spatio-temporally resolved model and averaged over pregnancy and the first year postpartum. Edinburgh Postnatal Depression Scale (EPDS) scores at 1 and 6 months were used to assess the relationship between PM(2.5) exposure and probable PPD (EPDS score ≥13) using relative risk regression and symptoms of anhedonia, depression, and anxiety (derived from EPDS subscales) using negative binomial regression. RESULTS: A 5-μg/m(3) increase in average PM(2.5) exposure during pregnancy was associated with an increased risk of PPD at 6 months (RR = 1.59; 95% CI: 1.11 to 2.28) and of late-onset PPD (no PPD at 1 month, PPD at 6 months) (RR = 2.58; 95% CI: 1.40 to 4.73) in covariate-adjusted models. No association was observed between PM(2.5) exposure in the first year postpartum and PPD. Average PM(2.5) exposure during pregnancy was also associated with increased 6-month EPDS subscale symptom scores for anhedonia (p = 0.03) and depression (p = 0.04). CONCLUSION: Our results suggest that in women in Mexico City, particulate matter exposure during pregnancy is positively associated with PPD and symptoms of anhedonia and depression at 6 months postpartum. Future studies should examine mechanisms linking air pollution and other environmental exposures during pregnancy with postpartum psychological functioning. 2019-11-21 2020-01 /pmc/articles/PMC7263529/ /pubmed/31760258 http://dx.doi.org/10.1016/j.envint.2019.105325 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ). |
spellingShingle | Article Niedzwiecki, Megan M. Rosa, Maria José Solano-González, Maritsa Kloog, Itai Just, Allan C. Martínez-Medina, Sandra Schnaas, Lourdes Tamayo-Ortiz, Marcela Wright, Robert O. Téllez-Rojo, Martha M. Wright, Rosalind J. Particulate air pollution exposure during pregnancy and postpartum depression symptoms in women in Mexico City |
title | Particulate air pollution exposure during pregnancy and postpartum depression symptoms in women in Mexico City |
title_full | Particulate air pollution exposure during pregnancy and postpartum depression symptoms in women in Mexico City |
title_fullStr | Particulate air pollution exposure during pregnancy and postpartum depression symptoms in women in Mexico City |
title_full_unstemmed | Particulate air pollution exposure during pregnancy and postpartum depression symptoms in women in Mexico City |
title_short | Particulate air pollution exposure during pregnancy and postpartum depression symptoms in women in Mexico City |
title_sort | particulate air pollution exposure during pregnancy and postpartum depression symptoms in women in mexico city |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263529/ https://www.ncbi.nlm.nih.gov/pubmed/31760258 http://dx.doi.org/10.1016/j.envint.2019.105325 |
work_keys_str_mv | AT niedzwieckimeganm particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity AT rosamariajose particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity AT solanogonzalezmaritsa particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity AT kloogitai particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity AT justallanc particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity AT martinezmedinasandra particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity AT schnaaslourdes particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity AT tamayoortizmarcela particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity AT wrightroberto particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity AT tellezrojomartham particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity AT wrightrosalindj particulateairpollutionexposureduringpregnancyandpostpartumdepressionsymptomsinwomeninmexicocity |