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Stocks of paracetamol products stored in urban New Zealand households: A cross-sectional study

BACKGROUND: Intentional self-harm is a common cause of hospital presentations in New Zealand and across the world, and self-poisoning is the most common method of self-harm. Paracetamol (acetaminophen) is frequently used in impulsive intentional overdoses, where ease of access may determine the choi...

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Autores principales: Kumpula, Eeva-Katri, Norris, Pauline, Pomerleau, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263603/
https://www.ncbi.nlm.nih.gov/pubmed/32479539
http://dx.doi.org/10.1371/journal.pone.0233806
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author Kumpula, Eeva-Katri
Norris, Pauline
Pomerleau, Adam C.
author_facet Kumpula, Eeva-Katri
Norris, Pauline
Pomerleau, Adam C.
author_sort Kumpula, Eeva-Katri
collection PubMed
description BACKGROUND: Intentional self-harm is a common cause of hospital presentations in New Zealand and across the world, and self-poisoning is the most common method of self-harm. Paracetamol (acetaminophen) is frequently used in impulsive intentional overdoses, where ease of access may determine the choice of substance. OBJECTIVE: This cross-sectional study aimed to determine how much paracetamol is present and therefore accessible in urban New Zealand households, and sources from where it has been obtained. This information is not currently available through any other means, but could inform New Zealand drug policy on access to paracetamol. METHODS: Random cluster-sampling of households was performed in major urban areas of two cities in New Zealand, and the paracetamol-containing products, quantities, and sources were recorded. Population estimates of proportions of various types of paracetamol products were calculated. RESULTS: A total of 174 of the 201 study households (86.6%) had at least one paracetamol product. Study households had mostly prescription products (78.2% of total mass), and a median of 24.0 g paracetamol present per household (inter-quartile range 6.0–54.0 g). Prescribed paracetamol was the main source of large stock. Based on the study findings, 53% of New Zealand households had 30 g or more paracetamol present, and 36% had 30 g or more of prescribed paracetamol, specifically. CONCLUSIONS: This study highlights the importance of assessing whether and how much paracetamol is truly needed when prescribing and dispensing it. Convenience of appropriate access to therapeutic paracetamol needs to be balanced with preventing unnecessary accumulation of paracetamol stocks in households and inappropriate access to it. Prescribers and pharmacists need to be aware of the risks of such accumulation and assess the therapeutic needs of their patients. Public initiatives should be rolled out at regular intervals to encourage people to return unused or expired medicines to pharmacies for safe disposal.
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spelling pubmed-72636032020-06-10 Stocks of paracetamol products stored in urban New Zealand households: A cross-sectional study Kumpula, Eeva-Katri Norris, Pauline Pomerleau, Adam C. PLoS One Research Article BACKGROUND: Intentional self-harm is a common cause of hospital presentations in New Zealand and across the world, and self-poisoning is the most common method of self-harm. Paracetamol (acetaminophen) is frequently used in impulsive intentional overdoses, where ease of access may determine the choice of substance. OBJECTIVE: This cross-sectional study aimed to determine how much paracetamol is present and therefore accessible in urban New Zealand households, and sources from where it has been obtained. This information is not currently available through any other means, but could inform New Zealand drug policy on access to paracetamol. METHODS: Random cluster-sampling of households was performed in major urban areas of two cities in New Zealand, and the paracetamol-containing products, quantities, and sources were recorded. Population estimates of proportions of various types of paracetamol products were calculated. RESULTS: A total of 174 of the 201 study households (86.6%) had at least one paracetamol product. Study households had mostly prescription products (78.2% of total mass), and a median of 24.0 g paracetamol present per household (inter-quartile range 6.0–54.0 g). Prescribed paracetamol was the main source of large stock. Based on the study findings, 53% of New Zealand households had 30 g or more paracetamol present, and 36% had 30 g or more of prescribed paracetamol, specifically. CONCLUSIONS: This study highlights the importance of assessing whether and how much paracetamol is truly needed when prescribing and dispensing it. Convenience of appropriate access to therapeutic paracetamol needs to be balanced with preventing unnecessary accumulation of paracetamol stocks in households and inappropriate access to it. Prescribers and pharmacists need to be aware of the risks of such accumulation and assess the therapeutic needs of their patients. Public initiatives should be rolled out at regular intervals to encourage people to return unused or expired medicines to pharmacies for safe disposal. Public Library of Science 2020-06-01 /pmc/articles/PMC7263603/ /pubmed/32479539 http://dx.doi.org/10.1371/journal.pone.0233806 Text en © 2020 Kumpula et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Kumpula, Eeva-Katri
Norris, Pauline
Pomerleau, Adam C.
Stocks of paracetamol products stored in urban New Zealand households: A cross-sectional study
title Stocks of paracetamol products stored in urban New Zealand households: A cross-sectional study
title_full Stocks of paracetamol products stored in urban New Zealand households: A cross-sectional study
title_fullStr Stocks of paracetamol products stored in urban New Zealand households: A cross-sectional study
title_full_unstemmed Stocks of paracetamol products stored in urban New Zealand households: A cross-sectional study
title_short Stocks of paracetamol products stored in urban New Zealand households: A cross-sectional study
title_sort stocks of paracetamol products stored in urban new zealand households: a cross-sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263603/
https://www.ncbi.nlm.nih.gov/pubmed/32479539
http://dx.doi.org/10.1371/journal.pone.0233806
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