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Comparison of biophysical properties of α1β2 and α3β2 GABA(A) receptors in whole-cell patch-clamp electrophysiological recordings

In the present study we have characterized the biophysical properties of wild-type (WT) α1β2 and α3β2 GABA(A) receptors and probed the molecular basis for the observed differences. The activation and desensitization behavior and the residual currents of the receptors expressed in HEK293 cells were d...

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Detalles Bibliográficos
Autores principales: Olander, Emma Rie, Janzen, Dieter, Villmann, Carmen, Jensen, Anders A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263626/
https://www.ncbi.nlm.nih.gov/pubmed/32479525
http://dx.doi.org/10.1371/journal.pone.0234080