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Polygonogram and isobolographic analysis of interactions between various novel antiepileptic drugs in the 6-Hz corneal stimulation-induced seizure model in mice

Pharmacotherapy with two antiepileptic drugs in combination is usually prescribed to epilepsy patients with refractory seizures. The choice of antiepileptic drugs in combination should be based on synergistic cooperation of the drugs with respect to suppression of seizures. The selection of synergis...

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Detalles Bibliográficos
Autores principales: Luszczki, Jarogniew J., Panasiuk, Anna, Zagaja, Mirosław, Karwan, Sławomir, Bojar, Hubert, Plewa, Zbigniew, Florek-Łuszczki, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263629/
https://www.ncbi.nlm.nih.gov/pubmed/32479532
http://dx.doi.org/10.1371/journal.pone.0234070