Cargando…
Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2
Sex differences in the incidence and progression of many liver diseases, including liver fibrosis and hepatocellular carcinoma, are associated with sex-biased hepatic expression of hundreds of genes. This sexual dimorphism is largely determined by the sex-specific pattern of pituitary growth hormone...
Autores principales: | Lau-Corona, Dana, Bae, Woo Kyun, Hennighausen, Lothar, Waxman, David J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263639/ https://www.ncbi.nlm.nih.gov/pubmed/32428001 http://dx.doi.org/10.1371/journal.pgen.1008796 |
Ejemplares similares
-
EZH2 Methyltransferase and H3K27 Methylation in Breast Cancer
por: Yoo, Kyung Hyun, et al.
Publicado: (2011) -
The Role of the Histone Methyltransferase EZH2 in Liver Inflammation and Fibrosis in STAM NASH Mice
por: Lee, Seul, et al.
Publicado: (2020) -
Cellular senescence primes liver fibrosis regression through Notch‐EZH2
por: Song, Ping, et al.
Publicado: (2023) -
Feminization of Male Mouse Liver by Persistent Growth Hormone Stimulation: Activation of Sex-Biased Transcriptional Networks and Dynamic Changes in Chromatin States
por: Lau-Corona, Dana, et al.
Publicado: (2017) -
The role of EZH1 and EZH2 in development and cancer
por: Lee, Soo Hyun, et al.
Publicado: (2022)