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A Genetic Screen for Human Genes Suppressing FUS Induced Toxicity in Yeast

FUS is a nucleic acid binding protein that, when mutated, cause a subset of familial amyotrophic lateral sclerosis (ALS). Expression of FUS in yeast recapitulates several pathological features of the disease-causing mutant proteins, including nuclear to cytoplasmic translocation, formation of cytopl...

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Detalles Bibliográficos
Autores principales:	Hayden, Elliott, Chen, Shuzhen, Chumley, Abagail, Xia, Chenyi, Zhong, Quan, Ju, Shulin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2020
Materias:	Mutant Screen Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263679/ https://www.ncbi.nlm.nih.gov/pubmed/32276960 http://dx.doi.org/10.1534/g3.120.401164

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