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MoBPS - Modular Breeding Program Simulator
The R-package MoBPS provides a computationally efficient and flexible framework to simulate complex breeding programs and compare their economic and genetic impact. Simulations are performed on the base of individuals. MoBPS utilizes a highly efficient implementation with bit-wise data storage and m...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263682/ https://www.ncbi.nlm.nih.gov/pubmed/32229505 http://dx.doi.org/10.1534/g3.120.401193 |
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author | Pook, Torsten Schlather, Martin Simianer, Henner |
author_facet | Pook, Torsten Schlather, Martin Simianer, Henner |
author_sort | Pook, Torsten |
collection | PubMed |
description | The R-package MoBPS provides a computationally efficient and flexible framework to simulate complex breeding programs and compare their economic and genetic impact. Simulations are performed on the base of individuals. MoBPS utilizes a highly efficient implementation with bit-wise data storage and matrix multiplications from the associated R-package miraculix allowing to handle large scale populations. Individual haplotypes are not stored but instead automatically derived based on points of recombination and mutations. The modular structure of MoBPS allows to combine rather coarse simulations, as needed to generate founder populations, with a very detailed modeling of todays’ complex breeding programs, making use of all available biotechnologies. MoBPS provides pre-implemented functions for common breeding practices such as optimum genetic contributions and single-step GBLUP but also allows the user to replace certain steps with personalized and/or self-written solutions. |
format | Online Article Text |
id | pubmed-7263682 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Genetics Society of America |
record_format | MEDLINE/PubMed |
spelling | pubmed-72636822020-06-08 MoBPS - Modular Breeding Program Simulator Pook, Torsten Schlather, Martin Simianer, Henner G3 (Bethesda) Software and Data Resources The R-package MoBPS provides a computationally efficient and flexible framework to simulate complex breeding programs and compare their economic and genetic impact. Simulations are performed on the base of individuals. MoBPS utilizes a highly efficient implementation with bit-wise data storage and matrix multiplications from the associated R-package miraculix allowing to handle large scale populations. Individual haplotypes are not stored but instead automatically derived based on points of recombination and mutations. The modular structure of MoBPS allows to combine rather coarse simulations, as needed to generate founder populations, with a very detailed modeling of todays’ complex breeding programs, making use of all available biotechnologies. MoBPS provides pre-implemented functions for common breeding practices such as optimum genetic contributions and single-step GBLUP but also allows the user to replace certain steps with personalized and/or self-written solutions. Genetics Society of America 2020-03-30 /pmc/articles/PMC7263682/ /pubmed/32229505 http://dx.doi.org/10.1534/g3.120.401193 Text en Copyright © 2020 Pook et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Software and Data Resources Pook, Torsten Schlather, Martin Simianer, Henner MoBPS - Modular Breeding Program Simulator |
title | MoBPS - Modular Breeding Program Simulator |
title_full | MoBPS - Modular Breeding Program Simulator |
title_fullStr | MoBPS - Modular Breeding Program Simulator |
title_full_unstemmed | MoBPS - Modular Breeding Program Simulator |
title_short | MoBPS - Modular Breeding Program Simulator |
title_sort | mobps - modular breeding program simulator |
topic | Software and Data Resources |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263682/ https://www.ncbi.nlm.nih.gov/pubmed/32229505 http://dx.doi.org/10.1534/g3.120.401193 |
work_keys_str_mv | AT pooktorsten mobpsmodularbreedingprogramsimulator AT schlathermartin mobpsmodularbreedingprogramsimulator AT simianerhenner mobpsmodularbreedingprogramsimulator |