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Homology modeling of TMPRSS2 yields candidate drugs that may inhibit entry of SARS-CoV-2 into human cells.

The most rapid path to discovering treatment options for the novel coronavirus SARS-CoV-2 is to find existing medications that are active against the virus. We have focused on identifying repurposing candidates for the transmembrane serine protease family member II (TMPRSS2), which is critical for e...

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Detalles Bibliográficos
Autores principales:	Rensi, Stefano, Keys, Allison, Lo, Yu-Chen, Derry, Alexander, McInnes, Greg, Liu, Tianyun, Altman, Russ
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	ChemRxiv 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263764/ https://www.ncbi.nlm.nih.gov/pubmed/32511288 http://dx.doi.org/10.26434/chemrxiv.12009582

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