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Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates

Host-virus arms races are inherently asymmetric; viruses evolve much more rapidly than host genomes. Thus, there is high interest in discovering mechanisms by which host genomes keep pace with rapidly evolving viruses. One family of restriction factors, the APOBEC3 (A3) cytidine deaminases, has unde...

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Detalles Bibliográficos
Autores principales: Yang, Lei, Emerman, Michael, Malik, Harmit S, McLaughlin, Richard N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263822/
https://www.ncbi.nlm.nih.gov/pubmed/32479260
http://dx.doi.org/10.7554/eLife.58436