High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals

The purpose of this study was to investigate the high-level mupirocin resistance (HLMR) in Gram-positive bacteria isolated from companion animals. A total of 931 clinical specimens were collected from diseased pets. The detection of mupirocin-resistant bacteria and plasmid-mediated mupirocin resista...

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Detalles Bibliográficos
Autores principales: Sum, Samuth, Park, Hee-Myung, Oh, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2020
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263919/
https://www.ncbi.nlm.nih.gov/pubmed/32476314
http://dx.doi.org/10.4142/jvs.2020.21.e40
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author Sum, Samuth
Park, Hee-Myung
Oh, Jae Young
author_facet Sum, Samuth
Park, Hee-Myung
Oh, Jae Young
author_sort Sum, Samuth
collection PubMed
description The purpose of this study was to investigate the high-level mupirocin resistance (HLMR) in Gram-positive bacteria isolated from companion animals. A total of 931 clinical specimens were collected from diseased pets. The detection of mupirocin-resistant bacteria and plasmid-mediated mupirocin resistance genes were evaluated by antimicrobial susceptibility tests, polymerase chain reactions, and sequencing analysis. Four-hundred and six (43.6%) bacteria were isolated and 17 (4.2%), including 14 staphylococci and 3 Corynebacterium were high-level mupirocin-resistant (MICs, ≥ 1,024 ug/mL) harboring mupA. Six staphylococci of HLMR strains had plasmid-mediated mupA-IS257 flanking regions. The results show that HLMR bacteria could spread in veterinary medicine in the near future.
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spelling pubmed-72639192020-06-10 High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals Sum, Samuth Park, Hee-Myung Oh, Jae Young J Vet Sci Rapid Communication The purpose of this study was to investigate the high-level mupirocin resistance (HLMR) in Gram-positive bacteria isolated from companion animals. A total of 931 clinical specimens were collected from diseased pets. The detection of mupirocin-resistant bacteria and plasmid-mediated mupirocin resistance genes were evaluated by antimicrobial susceptibility tests, polymerase chain reactions, and sequencing analysis. Four-hundred and six (43.6%) bacteria were isolated and 17 (4.2%), including 14 staphylococci and 3 Corynebacterium were high-level mupirocin-resistant (MICs, ≥ 1,024 ug/mL) harboring mupA. Six staphylococci of HLMR strains had plasmid-mediated mupA-IS257 flanking regions. The results show that HLMR bacteria could spread in veterinary medicine in the near future. The Korean Society of Veterinary Science 2020-05 2020-04-20 /pmc/articles/PMC7263919/ /pubmed/32476314 http://dx.doi.org/10.4142/jvs.2020.21.e40 Text en © 2020 The Korean Society of Veterinary Science https://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Rapid Communication
Sum, Samuth
Park, Hee-Myung
Oh, Jae Young
High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals
title High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals
title_full High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals
title_fullStr High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals
title_full_unstemmed High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals
title_short High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals
title_sort high-level mupirocin resistance in gram-positive bacteria isolated from diseased companion animals
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263919/
https://www.ncbi.nlm.nih.gov/pubmed/32476314
http://dx.doi.org/10.4142/jvs.2020.21.e40
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AT ohjaeyoung highlevelmupirocinresistanceingrampositivebacteriaisolatedfromdiseasedcompanionanimals

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