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Wntless regulates lipogenic gene expression in adipocytes and protects against diet-induced metabolic dysfunction
OBJECTIVE: Obesity is a key risk factor for many secondary chronic illnesses, including type 2 diabetes and cardiovascular disease. Canonical Wnt/β-catenin signaling is established as an important endogenous inhibitor of adipogenesis. This pathway is operative in mature adipocytes; however, its role...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264081/ https://www.ncbi.nlm.nih.gov/pubmed/32325263 http://dx.doi.org/10.1016/j.molmet.2020.100992 |