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Oxymatrine Attenuates Dopaminergic Neuronal Damage and Microglia-Mediated Neuroinflammation Through Cathepsin D-Dependent HMGB1/TLR4/NF-κB Pathway in Parkinson’s Disease

Oxymatrine (OMT), a natural quinoxaline alkaloid extracted from the root of Sophora ﬂavescens, presents amounts of pharmacological properties including immunomodulation, anti-inflammation, anti-oxidation, and anti-virus. Recent studies tend to focus on its effects on neuroinflammation and neuroprote...

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Detalles Bibliográficos
Autores principales:	Gan, Ping, Ding, Lidong, Hang, Guihua, Xia, Qiaofang, Huang, Zhimei, Ye, Xing, Qian, Xiaojuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264119/ https://www.ncbi.nlm.nih.gov/pubmed/32528295 http://dx.doi.org/10.3389/fphar.2020.00776

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