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Clearing method for 3-dimensional immunofluorescence of osteoarthritic subchondral human bone reveals peripheral cholinergic nerves

The cholinergic system plays a major anti-inflammatory role in many diseases through acetylcholine (Ach) release after vagus nerve stimulation. Osteoarthritis (OA) is associated with local low-grade inflammation, but the regulatory mechanisms are unclear. Local Ach release could have anti-inflammato...

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Detalles Bibliográficos
Autores principales:	Courties, Alice, Belle, Morgane, Senay, Simge, Cambon-Binder, Adeline, Sautet, Alain, Chédotal, Alain, Berenbaum, Francis, Sellam, Jérémie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264130/ https://www.ncbi.nlm.nih.gov/pubmed/32483280 http://dx.doi.org/10.1038/s41598-020-65873-6

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