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Glycan-dependent cell adhesion mechanism of Tc toxins

Toxin complex (Tc) toxins are virulence factors of pathogenic bacteria. Tcs are composed of three subunits: TcA, TcB and TcC. TcA facilitates receptor–toxin interaction and membrane permeation, TcB and TcC form a toxin-encapsulating cocoon. While the mechanisms of holotoxin assembly and pore formati...

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Detalles Bibliográficos
Autores principales: Roderer, Daniel, Bröcker, Felix, Sitsel, Oleg, Kaplonek, Paulina, Leidreiter, Franziska, Seeberger, Peter H., Raunser, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264150/
https://www.ncbi.nlm.nih.gov/pubmed/32483155
http://dx.doi.org/10.1038/s41467-020-16536-7

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