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Dysregulated Prefrontal Cortex Inhibition in Prepubescent and Adolescent Fragile X Mouse Model

Changes in excitation and inhibition are associated with the pathobiology of neurodevelopmental disorders of intellectual disability and autism and are widely described in Fragile X syndrome (FXS). In the prefrontal cortex (PFC), essential for cognitive processing, excitatory connectivity and plasti...

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Detalles Bibliográficos
Autores principales: Kramvis, Ioannis, van Westen, Rhodé, Lammertse, Hanna C. A., Riga, Danai, Heistek, Tim S., Loebel, Alex, Spijker, Sabine, Mansvelder, Huibert D., Meredith, Rhiannon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264168/
https://www.ncbi.nlm.nih.gov/pubmed/32528248
http://dx.doi.org/10.3389/fnmol.2020.00088