Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly

The functional study of lncRNAs in skeletal muscle satellite cells (SCs) remains at the infancy stage. Here we identify SAM (Sugt1 asssociated muscle) lncRNA that is enriched in the proliferating myoblasts. Global deletion of SAM has no overt effect on mice but impairs adult muscle regeneration foll...

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Detalles Bibliográficos
Autores principales: Li, Yuying, Yuan, Jie, Chen, Fengyuan, Zhang, Suyang, Zhao, Yu, Chen, Xiaona, Lu, Leina, Zhou, Liang, Chu, Ching Yan, Sun, Hao, Wang, Huating
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264179/
https://www.ncbi.nlm.nih.gov/pubmed/32483152
http://dx.doi.org/10.1038/s41467-020-16553-6

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