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Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis

Proteolytical processing of the growth factor VEGFC through the concerted activity of CCBE1 and ADAMTS3 is required for lymphatic development to occur. How these factors act together in time and space, and which cell types produce these factors is not understood. Here we assess the function of Adamt...

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Detalles Bibliográficos
Autores principales: Wang, Guangxia, Muhl, Lars, Padberg, Yvonne, Dupont, Laura, Peterson-Maduro, Josi, Stehling, Martin, le Noble, Ferdinand, Colige, Alain, Betsholtz, Christer, Schulte-Merker, Stefan, van Impel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264274/
https://www.ncbi.nlm.nih.gov/pubmed/32483144
http://dx.doi.org/10.1038/s41467-020-16552-7