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Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis
Proteolytical processing of the growth factor VEGFC through the concerted activity of CCBE1 and ADAMTS3 is required for lymphatic development to occur. How these factors act together in time and space, and which cell types produce these factors is not understood. Here we assess the function of Adamt...
Autores principales: | Wang, Guangxia, Muhl, Lars, Padberg, Yvonne, Dupont, Laura, Peterson-Maduro, Josi, Stehling, Martin, le Noble, Ferdinand, Colige, Alain, Betsholtz, Christer, Schulte-Merker, Stefan, van Impel, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264274/ https://www.ncbi.nlm.nih.gov/pubmed/32483144 http://dx.doi.org/10.1038/s41467-020-16552-7 |
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